US stocks were mixed in opening trade on Friday, held down by disappointing November foreign trade data and signs in Wells Fargo's quarterly earnings that its interest margin had tightened.
Five minutes into trade the Dow Jones Industrial Average was down 19.05 points (0.14 per cent) to 13,452.17.
The broadbased S&P 500 lost 1.28 (0.09 per cent) to 1470.84, while the Nasdaq Composite slipped 0.19 (0.01 per cent) to 3121.57.
Wells Fargo, the country's fourth largest bank, fell 2.0 per cent to $US34.68 ($A32.87) after its earnings beat analyst estimates but revealed that its net interest margins had narrowed.